Tools for Label-free Peptide Quantification
نویسندگان
چکیده
منابع مشابه
Tools for label-free peptide quantification.
The increasing scale and complexity of quantitative proteomics studies complicate subsequent analysis of the acquired data. Untargeted label-free quantification, based either on feature intensities or on spectral counting, is a method that scales particularly well with respect to the number of samples. It is thus an excellent alternative to labeling techniques. In order to profit from this scal...
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MOTIVATION Label-free quantification is an important approach to identify biomarkers, as it measures the quantity change of peptides across different biological samples. One of the fundamental steps for label-free quantification is to match the peptide features that are detected in two datasets to each other. Although ad hoc software tools exist for the feature matching, the definition of a com...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2013
ISSN: 1535-9476
DOI: 10.1074/mcp.r112.025163